Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | HCID 57936327 | HCID 57936327 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 57936238 | HCID 57936238 | — |
Reaction Steps
Compound of Example 156 (44 mg, 0.1 mmol) was dissolved in 2 ml ethanol and 100 mg (1.7 mmol) isopropylamine added. This mixture was stirred for 24 hours at 70° C. After evaporation the crude was purified by chromatography on silicagel (DCM/MeOH/ammonia:85/15/1.5). Yield: 38 mg (78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07615562B2 |
|---|
| Source dataset | uspto-grants-2009_11 |
|---|
| ORD ID | ord-86b2be7626dd480fa0407c1122b9bfb8 |
|---|
| Source note | uspto-grants-2009_11 |
|---|
