Benzo(B)Thiophene-2-Boronic Acid → HCID 57936254, compound

HRID 1434981Notes

Reaction equation

HRID 1434981 reaction equation
[S:1]1[C:5](B(O)O)=[CH:4][C:3]2[CH:9]=[CH:10][CH:11]=[CH:12][C:2]1=2.Cl[C:14]1[N:19]=[C:18](Cl)[C:17]([CH3:21])=[CH:16][N:15]=1.[NH2:22][CH:23]1[CH2:28][C:27]([CH3:30])([CH3:29])[NH:26][C:25]([CH3:32])([CH3:31])[CH2:24]1>>[S:1]1[C:5]([C:16]2[C:17]([CH3:21])=[CH:18][N:19]=[C:14]([NH:22][CH:23]3[CH2:24][C:25]([CH3:32])([CH3:31])[NH:26][C:27]([CH3:30])([CH3:29])[CH2:28]3)[N:15]=2)=[CH:4][C:3]2[CH:9]=[CH:10][CH:11]=[CH:12][C:2]1=2

Participants

4

Reactant 3

HCID 2359Benzo(B)Thiophene-2-Boronic AcidHCID 375244-Amino-2,2,6,6-tetramethylpiperidineHCID 74508Pyrimidine, 2,4-dichloro-5-methyl-

Product 1

HCID 57936254HCID 57936254, compound

Procedure

The title compound was prepared analogous to Steps B and C of Method A, starting from benzo[b]thiophene-2-boronic acid, 2,4-dichloro-5-methyl-pyrimidine and 4-amino-2,2,6,6-tetramethylpiperidine.

Sources & evidence

ORD record
ord-5db8653dcf4b42a3b385a22ae9c49cfd
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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