HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Carboxyethyl)benzeneboronic acid → 3-{4-[2-(2,2,6,6-Tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-phenyl}-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Carboxyethyl)benzeneboronic acid | HCID 3863484 | — |
| Reactant | (4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amine | HCID 57936167 | — |
| Product | 3-{4-[2-(2,2,6,6-Tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-phenyl}-propionic acid | HCID 57936234 | — |
Reaction Steps
The title compound was prepared from (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine and 4-(2-carboxyethyl)phenylboronic acid according to Method C (Example 178). Yield: 1.4 g (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615562B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-673937be3b3447019c0a4b2c8c9f4445 |
| Source note | uspto-grants-2009_11 |