4-Toluenesulfonyl chloride → HCID 57936113, compound

HRID 1435017Notes

Reaction equation

HRID 1435017 reaction equation
[CH3:1][C:2]1([CH3:27])[CH2:7][CH:6]([NH:8][C:9]2[N:14]=[C:13]([C:15]3[CH:20]=[CH:19][C:18]([CH2:21][CH:22]([OH:24])[CH3:23])=[CH:17][CH:16]=3)[CH:12]=[CH:11][N:10]=2)[CH2:5][C:4]([CH3:26])([CH3:25])[NH:3]1.[C:28]1([CH3:38])[CH:33]=[CH:32][C:31]([S:34](Cl)(=[O:36])=[O:35])=[CH:30][CH:29]=1>N1C=CC=CC=1>[CH3:23][CH:22]([O:24][S:34]([C:31]1[CH:32]=[CH:33][C:28]([CH3:38])=[CH:29][CH:30]=1)(=[O:36])=[O:35])[CH2:21][C:18]1[CH:19]=[CH:20][C:15]([C:13]2[CH:12]=[CH:11][N:10]=[C:9]([NH:8][CH:6]3[CH2:5][C:4]([CH3:26])([CH3:25])[NH:3][C:2]([CH3:1])([CH3:27])[CH2:7]3)[N:14]=2)=[CH:16][CH:17]=1

Participants

4

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 57936239HCID 57936239, compound

Product 1

HCID 57936113HCID 57936113, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The title compound was prepared from 1-{4-[2-(2,2,6,6-tetramethyl-piperidin-4-ylamino)-pyrimidin-4-yl]-phenyl}-propan-2-ol and p-toluenesulfonyl chloride in pyridine. Yield: 177 mg (100%).

Sources & evidence

ORD record
ord-afd7710d19ec4241ab2f22f9300a2c61
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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