HCID 57936344, compound → HCID 57936182, compound

HRID 1435019Notes

Reaction equation

HRID 1435019 reaction equation
[N:1]([CH:4]([CH3:29])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][N:15]=[C:14]([NH:18][CH:19]3[CH2:24][C:23]([CH3:26])([CH3:25])[NH:22][C:21]([CH3:28])([CH3:27])[CH2:20]3)[N:13]=2)=[CH:8][CH:7]=1)=[N+]=[N-]>CO.O=[Pt]=O>[NH2:1][CH:4]([CH3:29])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][N:15]=[C:14]([NH:18][CH:19]3[CH2:24][C:23]([CH3:26])([CH3:25])[NH:22][C:21]([CH3:28])([CH3:27])[CH2:20]3)[N:13]=2)=[CH:8][CH:7]=1

Participants

4

Reactant 1

HCID 57936344HCID 57936344, compound

Product 1

HCID 57936182HCID 57936182, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 887MethanolSolvent

Procedure

The title compound was prepared from {4-[4-(2-azido-propyl)-phenyl]-pyrimidin-2-yl}-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine by hydrogenation using PtO2 in MeOH. Yield: 38 mg (81%).

Sources & evidence

ORD record
ord-490de8f2ea5f47d78ce640bf2ce74ef0
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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