HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amine → HCID 57936296, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Chloro-pyrimidin-2-yl)(2,2,6,6-tetramethyl-piperidin-4-yl)-amine | HCID 57936167 | — |
| Reactant | HCID 69061243 | HCID 69061243 | — |
| Product | HCID 57936296 | HCID 57936296 | — |
Reaction Steps
The title compound was prepared as described in Example 215, starting from {2-[1-(tert-butyl-dimethyl-silanyl)-1H-indol-6-yl]-1-methyl-ethyl}-trityl-amine (prepared by trityl and TBDMS protection of 2-(1H-Indol-6-yl)-1-methyl-ethylamine) and (4-chloro-pyrimidin-2-yl)-(2,2,6,6-tetramethyl-piperidin-4-yl)-amine, followed by in situ removal of the protecting groups with 2N-HCl. Yield: 406 mg (31%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615562B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-b1e73572c6154c068a9bedb44a63ca24 |
| Source note | uspto-grants-2009_11 |