HCID 57937845, compound → HCID 57937842, compound

Participants

Reaction Steps

2′-Chloro-4′-hydroxymethyl-biphenyl-3-carboxylic acid amide (I-6d: 5.0 g) was suspended in 500 mL of ethyl acetate and treated with activated manganese dioxide (5 equivalents). After stirring for 12 hours, the reaction mixture was filtered through a pad of Celite and concentrated under reduced pressure to afford the title compound (I-6e).

Provenance & Evidence