HCID 57937843, compound → HCID 57937815, compound

Participants

Reaction Conditions

Reaction Steps

(3′-Carbamoyl-2-fluoro-biphenyl-4-ylmethyl)-(3-methyl-butyl)-carbamic acid tert-butyl ester (I-5e; 0.8 g, 1.92 mmol) was dissolved in dimethylformamide dimethyl acetal (10 ml) and heated to 120° C. for 2 hours. The reaction mixture was then cooled to room temperature and volatiles were removed under reduced pressure. The crude residue (0.9 g) used in the next reaction without purification. Mass Spec.: (m/z+1=470).

Provenance & Evidence