HCID 57937834, compound → HCID 57937838, compound

Participants

Reaction Steps

(3-Methyl-butyl)-(2-methyl-4′-nitro-biphenyl-4-ylmethyl)-carbamic acid tert-butyl ester (I-9a: 0.150 mg, 0.364 mmol) in methanol (12.1 ml) was hydrogenated employing an H-cube apparatus (atmospheric pressure, flow rate=1 mL/min, hydrogen level=full hydrogen, temperature=35° C.). The reaction mixture was allowed to proceed through a palladium on carbon cartridge and the contents collected and concentrated under reduced pressure. The resulting title compound (I-8b) was carried on to the next reaction without further purification.

Provenance & Evidence