Ethanethiol → HCID 15074080, compound

HRID 1435091Notes

Reaction equation

HRID 1435091 reaction equation
Br[C:2]([CH3:9])([CH3:8])[C:3]([O:5][CH2:6][CH3:7])=[O:4].[CH2:10]([SH:12])[CH3:11].[OH-].[K+]>C(O)C>[CH2:6]([O:5][C:3](=[O:4])[C:2]([S:12][CH2:10][CH3:11])([CH3:9])[CH3:8])[CH3:7]

Participants

5

Reactant 3

HCID 6343EthanethiolHCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 14797Potassium Hydroxide

Product 1

HCID 15074080HCID 15074080, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethyl 2-bromoisobutyrate (28.6, 0.146 mole), ethanethiol (100 g, 0.161 mole), potassium hydroxide (10.3 g, 0.161 mole), ethyl alcohol. Stirred reaction mixture for two hours at room temperature prior to quenching. Crude yield: 117%; after kugelrohr: 77.8%.

Workup

  1. customreaction mixture for two hours at room temperature
  2. customto quenching

Sources & evidence

ORD record
ord-caf3534d23a74cbf8d4df74efea50d8d
Source dataset
uspto-grants-2009_11
Patent number
US07615661B2

Reaction notes

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