HuagongsheHuagongshe Chemistry Print Report · For research reference only
Z-D-Trp-Lys(BOC)-OMe → H-D-Trp-Lys(BOC)-OMe
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Z-D-Trp-Lys(BOC)-OMe | HCID 57936723 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | H-D-Trp-Lys(BOC)-OMe | HCID 15480274 | — |
Reaction Steps
19.8 (34.1 mmol) g Z-D-Trp-Lys(BOC)-OMe are dissolved in 220 ml methanol, 2.2 g catalyst PdC 10% added and hydrogenated at RT. The hydrogenation is finished after 1 hour at RT, the catalyst filtered off and the filtrate evaporated at 30°: white solid. HPLC: 98.1% b.a. (16.2 min).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07615609B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-73ced55a3db645b6aa5a8feb66a8b082 |
| Source note | uspto-grants-2009_11 |