Potassium hydroxy sulfite → HCID 178441540, compound

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Reaction Steps

1-({2-tert-Butyl-1-[(trans-4-fluorocyclohexyl)methyl]-1H-benzimidazol-5-yl}sulfonyl)-1H-pyrazole-4-carbaldehyde (130 mg, 0.291 mmol) and oxone (215 mg, 0.349 mmol) were stirred in 10 mL of DMF at rt overnight. The solvent was evaporated. The residue was dissolved in DCM and washed with water, brine and dried over anhydrous MgSO4. Yield: 135 mg (99%). MS (ESI) (M+H)+=463.06.

Provenance & Evidence