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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435541Generated: October 26, 2026

Ethylamine → N-ethyl-5-methyl-1H-pyrazole-4-carboxamide

https://huagongshe.com/reaction/1435541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
Reactant5-methyl-1H-pyrazole-4-carboxylic acidHCID 557600—
ProductN-ethyl-5-methyl-1H-pyrazole-4-carboxamideHCID 178464939100%

Reaction Steps

Following the same procedure in Example 29 (Steps B and C in Method B), using 3-methyl-1H-pyrazole-4-carboxylic acid (252 mg, 2.0 mmol) and ethylamine (225 mg, 5.0 mmol), provided the desired crude compound (306 mg, 100%), which was used in Step A directly.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07615642B2
Source datasetuspto-grants-2009_11
ORD IDord-354feb8571ca4f4cacd1d39c44c04773
Source noteuspto-grants-2009_11