Diethyl Ether → HCID 178524330, compound

HRID 1435581Notes

Reaction equation

HRID 1435581 reaction equation
[C:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH:7]=O)([OH:3])=[O:2].[NH2:12][C:13]1[C:18]([NH2:19])=[CH:17][C:16]([N+:20]([O-:22])=[O:21])=[CH:15][N:14]=1.C(OCC)(=O)C.C(OCC)C>[N+](C1C=CC=CC=1)([O-])=O>[N+:20]([C:16]1[CH:17]=[C:18]2[N:19]=[C:7]([C:6]3[CH:5]=[C:4]([CH:11]=[CH:10][CH:9]=3)[C:1]([OH:3])=[O:2])[NH:12][C:13]2=[N:14][CH:15]=1)([O-:22])=[O:21]

Participants

6

Reactant 4

HCID 3283Diethyl EtherHCID 8857Ethyl AcetateHCID 120773-CarboxybenzaldehydeHCID 34801515-Nitropyridine-2,3-diamine

Product 1

HCID 178524330HCID 178524330, compound

Reagents, catalysts & solvents 1

HCID 7416NitrobenzeneSolvent

Procedure

0.87 g 3-carboxybenzaldehyde and 0.866 g 2,3-diamino-5-nitropyridine in 50 ml nitrobenzene were heated to 160° C. for 30 hrs. The mixture was cooled to room temperature and 200 ml ethyl acetate and 100 ml ethyl ether were added. The precipitated product was collected by filtration and dried. Yield 1.135 g

Workup

  1. filtrationThe precipitated product was collected by filtration
  2. customdried

Sources & evidence

ORD record
ord-10186833e9684bb3afa2f097f8cf94df
Source dataset
uspto-grants-2009_11
Patent number
US07618964B2

Reaction notes

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