Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1435615Generated: October 27, 2026

4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl (2-{[(3-methylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate

https://huagongshe.com/reaction/1435615

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Thiazoleacetic acid, 2-amino-, ethyl esterHCID 104454—
Reactant3-Methylbenzenesulphonyl chlorideHCID 2734595—
ProductEthyl (2-{[(3-methylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetateHCID 10268844—

Reaction Steps

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 3-methylbenzenesulfonyl chloride according to METHOD A, giving 0.51 g (75%) of a pink powder: MS (electrospray, [M−H]−) m/z 339.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618961B2
Source datasetuspto-grants-2009_11
ORD IDord-2d3f90e51fe74c3cb840fe3441bc3666
Source noteuspto-grants-2009_11