4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl (2-{[(4-butoxyphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate

Participants

Role	Name	HCID	Charge
Reactant	4-Thiazoleacetic acid, 2-amino-, ethyl ester	HCID 104454	—
Reactant	4-Butoxybenzenesulfonyl Chloride	HCID 517990	—
Product	Ethyl (2-{[(4-butoxyphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate	HCID 10294305	—

Reaction Steps

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 4-n-butoxybenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (11.8 mg) with purity >90%. LCMS (pos) m/z 399.2.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07618961B2
Source dataset	uspto-grants-2009_11
ORD ID	ord-16572dedbf134a5f90677bc98b2f1322
Source note	uspto-grants-2009_11