2,3,4-Trichlorobenzenesulfonyl chloride → HCID 10181071, compound

HRID 1435655Notes

Reaction equation

HRID 1435655 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[Cl:13][C:14]1[C:19]([Cl:20])=[C:18]([Cl:21])[CH:17]=[CH:16][C:15]=1[S:22](Cl)(=[O:24])=[O:23]>>[Cl:13][C:14]1[C:19]([Cl:20])=[C:18]([Cl:21])[CH:17]=[CH:16][C:15]=1[S:22]([NH:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1)(=[O:24])=[O:23]

Participants

3

Reactant 2

HCID 369042,3,4-Trichlorobenzenesulfonyl chlorideHCID 1044544-Thiazoleacetic acid, 2-amino-, ethyl ester

Product 1

HCID 10181071HCID 10181071, compound

Procedure

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 2,3,4-trichlorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (51.9 mg) with purity >90%. MS (pos) m/z 429.0, 431.0, 433.0.

Sources & evidence

ORD record
ord-19e90494621f49bfa3583fffc94954e4
Source dataset
uspto-grants-2009_11
Patent number
US07618961B2

Reaction notes

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