4-Thiazoleacetic acid, 2-amino-, ethyl ester → Ethyl [2-({[5-(3-isoxazolyl)-2-thienyl]sulfonyl}amino)-1,3-thiazol-4-yl]acetate

Participants

Role	Name	HCID	Charge
Reactant	4-Thiazoleacetic acid, 2-amino-, ethyl ester	HCID 104454	—
Reactant	5-(Isoxazol-3-yl)thiophene-2-sulfonyl chloride	HCID 2797180	—
Product	Ethyl [2-({[5-(3-isoxazolyl)-2-thienyl]sulfonyl}amino)-1,3-thiazol-4-yl]acetate	HCID 10200946	—

Reaction Steps

The title compound was prepared from ethyl 2-amino-4-thiazolylacetate and 5-isoxazol-3-ylthiophene-2-sulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (15.9 mg) with purity >90%. MS (pos) m/z 400.3.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07618961B2
Source dataset	uspto-grants-2009_11
ORD ID	ord-76bb9397247048ca8a56e913c8d3a742
Source note	uspto-grants-2009_11