HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4,6-Trichlorobenzenesulfonyl chloride → Ethyl oxo(2-{[(2,4,6-trichlorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4,6-Trichlorobenzenesulfonyl chloride | HCID 521335 | — |
| Reactant | Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate | HCID 4356513 | — |
| Product | Ethyl oxo(2-{[(2,4,6-trichlorophenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate | HCID 10138353 | — |
Reaction Steps
The title compound was prepared from ethyl (2-amino-4-thiazolyl)glyoxylate and 2,4,6-trichlorobenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (18.3 mg) with purity >80%. LCMS (pos) m/z 445.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618961B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-a68f2aff9dae4daa92bf02385b1de063 |
| Source note | uspto-grants-2009_11 |