HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1,1'-Biphenyl)-4-sulphonyl chloride → Ethyl {2-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-1,3-thiazol-4-yl}(oxo)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1,1'-Biphenyl)-4-sulphonyl chloride | HCID 74192 | — |
| Reactant | Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate | HCID 4356513 | — |
| Product | Ethyl {2-[([1,1'-biphenyl]-4-ylsulfonyl)amino]-1,3-thiazol-4-yl}(oxo)acetate | HCID 10295384 | — |
Reaction Steps
The title compound was prepared from ethyl (2-amino-4-thiazolyl)glyoxylate and 4-phenylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a yellow solid (28.2 mg) with purity >80%. LCMS (pos) m/z 417.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618961B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-de594e43429f4eb49ac5316b68db3838 |
| Source note | uspto-grants-2009_11 |