HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate → Methyl (2-{[(2,4-dichloro-6-methylphenyl)sulfonyl]amino}-5-methyl-1,3-thiazol-4-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate | HCID 2763571 | — |
| Reactant | 2,4-Dichloro-6-methylbenzenesulfonyl chloride | HCID 2801387 | — |
| Product | Methyl (2-{[(2,4-dichloro-6-methylphenyl)sulfonyl]amino}-5-methyl-1,3-thiazol-4-yl)acetate | HCID 86594955 | — |
Reaction Steps
The title compound was prepared from methyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate and 2,4-dichloro-6-methylbenzenesulfonyl chloride as described in the synthetic METHOD B to give a white solid (27.2 mg) with purity >80%. MS (pos) m/z 409.0, 411.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618961B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-9def2a3654674a32b3e6898457bfe6f7 |
| Source note | uspto-grants-2009_11 |