HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-Oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazine-7-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 2-oxo-2,3-dihydro-1h-pyrido[2,3-b][1,4]thiazine-7-carboxylate | HCID 17981264 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazine-7-carboxylic acid | HCID 21873692 | 95.2% |
Reaction Steps
2-Oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazine-7-carboxylic acid methyl ester (2.8 g) was hydrolyzed with aqueous sodium hydroxide in tetrahydrofuran by the method of Preparation (14a) to afford a solid (2.5 g). MS (−ve ion electrospray) m/e 209 (M−H−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618959B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-0ed83751c27f4186bd16e382ef7600a2 |
| Source note | uspto-grants-2009_11 |