tert-Butyl (3S)-3-hydroxypyrrolidine-1-carboxylate → HCID 68875035, compound

Participants

Reaction Steps

This compound was prepared from (S)-3-hydroxypyrrolidine-1-carboxylic acid tert-butyl ester (195 mg, 1.04 mmol) and 1-amino-6-hydroxyisoquinoline (200 mg, 1.25 mmol) by the Mitsunobu procedure described in 3C, subsequent Boc deprotection according to procedure described in 3D gave (S)-6-(pyrrolidin-3-yloxy)-isoquinolin-1-ylamine, El-MS: m/z=230.3 [M+H]+.

Provenance & Evidence