HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-6-(piperidin-3-yloxy)-2H-isoquinolin-1-one → 7-Methyl-6-(piperidin-3-yloxy)-2H-isoquinolin-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-6-(piperidin-3-yloxy)-2H-isoquinolin-1-one | HCID 16124479 | — |
| Reactant | tert-Butyl (3R)-3-[(methanesulfonyl)oxy]piperidine-1-carboxylate | HCID 29939737 | — |
| Reactant | 6-Hydroxy-7-methylisoquinolin-1(2H)-one | HCID 68875512 | — |
| Product | 7-Methyl-6-(piperidin-3-yloxy)-2H-isoquinolin-1-one | HCID 57652421 | — |
Reaction Steps
Prepared according to Example 24C and 24D using (R)-3-methanesulphonyloxy-piperidine-1-carboxylic acid tert-butyl ester and 6-hydroxy-7-methyl-2H-isoquinolin-1-one to afford 7-Methyl-6-(piperidin-3-yloxy)-2H-isoquinolin-1-one El-MS: m/z=259.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618985B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-a02de5b066be46a7935f5f3d13176a41 |
| Source note | uspto-grants-2009_11 |