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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436056Generated: October 31, 2026

(r/s)-3-(Tert-butoxycarbonyl)amino-1-(1-amino-4-chloro-5-isoquinolinesulfonyl)-pyrrolidine → Hydrochloric Acid

https://huagongshe.com/reaction/1436056

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(r/s)-3-(Tert-butoxycarbonyl)amino-1-(1-amino-4-chloro-5-isoquinolinesulfonyl)-pyrrolidineHCID 67243409—
Reactant(r/s)-3-(Tert-butoxycarbonylamino)-1-(1-chloro-4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 87322137—
ProductHydrochloric AcidHCID 313—
Product(r/s)-3-Amino-1-(1-amino-4-bromo-5-isoquinolinesulfonyl)pyrrolidineHCID 67243187—

Reaction Steps

Intermediate 29 is used in the method of Example 39, Step B instead of Intermediate 28 to obtain the title compound as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618984B2
Source datasetuspto-grants-2009_11
ORD IDord-7d44d34b8b9847d9be7af8cf5a5c6262
Source noteuspto-grants-2009_11