Hydrogen Bromide → HCID 17967165, compound

Participants

Reaction Steps

300 mg of (2R/S)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-7-methoxychroman is treated with 25 ml hydrobromic acid (48% in water) at 130 degrees C. The obtained red solution is neutralized and worked up as described in example 1. 130 mg of (2R/S)-2-({[5-(4-fluorophenyl)-pyridin-3ylmethyl]-amino}-methyl)-chroman-7-ol hydrobromide is obtained;

Provenance & Evidence