HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 57938806, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | (2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methylamine | HCID 11558497 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 57938806 | HCID 57938806 | — |
Reaction Steps
The title compound was prepared from (2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methylamine (10 mg, 0.030 mmol) and 7 M ammonia in methanol (1 mL) by a procedure similar to example 10 (3 mg, 30%). 1H NMR (CDCl3): 8.04 (dd, J=2.9, 0.6 Hz, 1H), 7.49-7.43 (m, 2H), 7.39 (dd, J=5.7 and 2.7 Hz, 1H), 6.92 (brd, J=8.4 Hz, 1H), 6.85-6.78 (m, 2H), 5.65 (s, 2H), 3.96 (s, 3H), 3.54 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618975B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-d1a6bae7394d4a68a4264e555fd056e6 |
| Source note | uspto-grants-2009_11 |