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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436256Generated: November 1, 2026

Ammonia → HCID 57938806, compound

https://huagongshe.com/reaction/1436256

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant(2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methylamineHCID 11558497—
SolventMethanolHCID 887—
ProductHCID 57938806HCID 57938806—

Reaction Steps

The title compound was prepared from (2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methylamine (10 mg, 0.030 mmol) and 7 M ammonia in methanol (1 mL) by a procedure similar to example 10 (3 mg, 30%). 1H NMR (CDCl3): 8.04 (dd, J=2.9, 0.6 Hz, 1H), 7.49-7.43 (m, 2H), 7.39 (dd, J=5.7 and 2.7 Hz, 1H), 6.92 (brd, J=8.4 Hz, 1H), 6.85-6.78 (m, 2H), 5.65 (s, 2H), 3.96 (s, 3H), 3.54 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618975B2
Source datasetuspto-grants-2009_11
ORD IDord-d1a6bae7394d4a68a4264e555fd056e6
Source noteuspto-grants-2009_11