Ethanolamine → HCID 14088361, compound

HRID 1436356Notes

Reaction equation

HRID 1436356 reaction equation
[CH2:1]([CH2:3][NH2:4])[OH:2].C[O:6][C:7](=O)[CH:8]([Cl:10])[CH3:9]>>[Cl:10][CH:8]([CH3:9])[C:7]([NH:4][CH2:3][CH2:1][OH:2])=[O:6]

Participants

3

Reactant 2

HCID 700EthanolamineHCID 28659Methyl 2-chloropropionate

Product 1

HCID 14088361HCID 14088361, compoundYield 91.5%

Procedure

Ethanolamine (13.45 g, 0.22 mol) is added to 21.5 ml (0.2 mol) of 2-chloropropionic acid methylester. The mixture solidifies after standing at room temperature for 60 h. The solid is triturated with ethylacetate, the crystals are filtered off and dried to afford 27.75 g of the title compound as white crystals, mp. 64° C.

Workup

  1. customThe solid is triturated with ethylacetate
  2. filtrationthe crystals are filtered off
  3. customdried

Sources & evidence

ORD record
ord-90585022ac264aae91cafcc4fef8a412
Source dataset
uspto-grants-2009_11
Patent number
US07619050B2

Reaction notes

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