反应详情

Add 2-(S)-dibenzylamino-3-phenyl-1-pyridin-2-yl-propan-1-(S)-ol (1.05 g, 2.57 mmol), 5% platinum on carbon sulfided (215 mg), glacial acetic acid (2 mL) and methanol (40 mL) and stir 18 h under 1 atmosphere of hydrogen gas. Add filter agent, filter and concentrate. Add ethyl acetate and wash with saturated aqueous sodium bicarbonate, dry (magnesium sulfate) and concentrate to give the title compound as a white foam (1.005 g, 94%).

1. additionAdd
2. filtrationfilter agent
3. filtrationfilter
4. concentrationconcentrate
5. washAdd ethyl acetate and wash with saturated aqueous sodium bicarbonate
6. dry with materialdry (magnesium sulfate)
7. concentrationconcentrate