HRID1436521

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=CC(Cc1cc(F)cc(F)c1)N(Cc1ccccc1)Cc1ccccc1

HCID58622433

未命名化合物

结构：CC(C)CCc1ccccc1N1CCN(C(=O)OC(C)(C)C)CC1=O

HCID69017615

未命名化合物

PRODUCTS

生成物

结构：CC(C)CCc1ccccc1N1CCN(C(=O)OC(C)(C)C)[C@@H]([C@@H](O)[C@@H](N)Cc2cc(F)cc(F)c2)C1=O

HCID69015910

未命名化合物

PROCEDURE

实验过程

The title is prepared by reacting 4-[2-(3-methyl-butyl)-phenyl]-3-oxo-piperazine-1-carboxylic acid tert-butyl ester with 2-(dibenzylamino)-3-(3,5-difluorophenyl)-propanal essentially as described in Preparation 41.

WORKUP

后处理

customThe title is prepared
customas described in Preparation 41

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1a3a372096624bfaa657a10174cfa929
来源数据集: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07618978B2
来源说明: uspto-grants-2009_11

反应 SMILES

[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[CH2:20][CH2:21][CH:22]([CH3:24])[CH3:23])[C:10](=[O:25])[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].C([N:33](CC1C=CC=CC=1)[CH:34]([CH2:37][C:38]1[CH:43]=[C:42]([F:44])[CH:41]=[C:40]([F:45])[CH:39]=1)[CH:35]=[O:36])C1C=CC=CC=1>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[CH2:20][CH2:21][CH:22]([CH3:23])[CH3:24])[C:10](=[O:25])[C@@H:9]1[C@@H:35]([OH:36])[C@@H:34]([NH2:33])[CH2:37][C:38]1[CH:39]=[C:40]([F:45])[CH:41]=[C:42]([F:44])[CH:43]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]