HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorosulfonic acid → 3-Bromo-4-fluoro-5-(chlorosulfonyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorosulfonic acid | HCID 24638 | — |
| Reactant | 3-Bromo-4-fluorobenzoic acid | HCID 70509 | — |
| Product | 3-Bromo-4-fluoro-5-(chlorosulfonyl)benzoic acid | HCID 50998480 | — |
Reaction Steps
Heat 3-bromo-4-fluorobenzoic acid (6.25 g, 26.2 mmol) in chlorosulfonic acid (15 mL) at 125° C. for 120 h. Cool to room temperature and add dropwise to about 125 mL ice water. Collect the filtered solid as the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618978B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-482e5b46ba1b43518b84a133d311a127 |
| Source note | uspto-grants-2009_11 |