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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1436744Generated: October 29, 2026

Hydrochloric Acid → HCID 69017376, compound

https://huagongshe.com/reaction/1436744

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 86615388HCID 86615388—
ProductHCID 69017376HCID 6901737692%

Reaction Steps

Add 4.0 M hydrogen chloride in dioxane (0.46 mL, 1.86 mmoles) to (2R, 5R)-2-{(4S, 5S)-3-Acetyl-4-[3,5-difluoro-benzyl]-2,2-dimethyl-oxazolidin-5-yl}-5-(3-methyl-butoxy)-piperidine-1-carboxylic acid tert-butyl ester (0.05 g, 0.09 mmol) and stir until all starting material is consumed. Concentrate to afford the title product as a white solid (0.04 g, 92%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07618978B2
Source datasetuspto-grants-2009_11
ORD IDord-8fcbeba2d484403ba427f0fe3ddbdbbe
Source noteuspto-grants-2009_11