HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 69017376, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 86615388 | HCID 86615388 | — |
| Product | HCID 69017376 | HCID 69017376 | 92% |
Reaction Steps
Add 4.0 M hydrogen chloride in dioxane (0.46 mL, 1.86 mmoles) to (2R, 5R)-2-{(4S, 5S)-3-Acetyl-4-[3,5-difluoro-benzyl]-2,2-dimethyl-oxazolidin-5-yl}-5-(3-methyl-butoxy)-piperidine-1-carboxylic acid tert-butyl ester (0.05 g, 0.09 mmol) and stir until all starting material is consumed. Concentrate to afford the title product as a white solid (0.04 g, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07618978B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-8fcbeba2d484403ba427f0fe3ddbdbbe |
| Source note | uspto-grants-2009_11 |