反应详情

2-Methyl-3-nitro-N,N-Di-n-propyl phenyl ethyl ammonium oxalate (100 g) is added to solution of Sodium hydroxide (2000 ml 1.4%) and stir until the clear solution is obtained. Further, ethyl acetate (500 ml) is added and organic layer separated out, washed with brine solution and dried over Sodium sulphate (20 gm). Ethyl acetate is distilled out under vacuum at 50-60° C. to get residue of 2-Methyl-3-nitro-N,N-di-n-propyl phenyl ethyl amine as a free base (70-72 g)

1. customis obtained
2. customorganic layer separated out
3. washwashed with brine solution
4. dry with materialdried over Sodium sulphate (20 gm)
5. distillationEthyl acetate is distilled out under vacuum at 50-60° C.