N,N-Dimethylethylenediamine → HCID 178483757, compound

HRID 1437005Notes

Reaction equation

HRID 1437005 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[C:8](=O)[NH:7][C:6]=2[CH:17]=1.[CH3:18][N:19]([CH3:23])[CH2:20][CH2:21][NH2:22]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[C:8]([NH:22][CH2:21][CH2:20][N:19]([CH3:23])[CH3:18])=[N:7][C:6]=2[CH:17]=1

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 36531168-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one

Product 1

HCID 178483757HCID 178483757, compoundYield 63.5%

Procedure

8-Chloro-5,10-dihydro-dibenzo[b,e][1,4]diazepine-11-one (25 mg, 0.1 mmol) and N,N-dimethylethylenediamine (44 mg, 0.5 mmol) were reacted according to GP4 to give 20 mg of the title compound (160FE16D). MS (ESI) 315 (MH+). Purity for MH+ (UV/MS) 100/100.

Sources & evidence

ORD record
ord-076c0f14a9754f05befb092eccb957e6
Source dataset
uspto-grants-2009_11
Patent number
US07622461B2

Reaction notes

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