Acetone → HCID 178443389, compound

Participants

Reaction Steps

25 ml of methanol, 40 ml of acetone and 0.1 ml of concentrated hydrochloric acid were added to 1.9 g (4.5 mmol) of N1-(4-hydroxybenzyl)-N5-decyl-biguanide dihydrochloride, and the mixture was refluxed for 30 hours. The solvent was distilled off under reduced pressure, and the residue was recrystallized with 80% aqueous acetonitrile to obtain 0.4 g of colorless crystals having a melting point of 109 to 111° C.

Provenance & Evidence