Hydrochloric Acid → HCID 69061731, compound

Participants

Reaction Steps

100 ml of ethanol, 4.4 ml (25.6 mmol) of 1-nonanal, and 0.7 ml of concentrated hydrochloric acid were added to 5.0 g (16.8 mmol) of N1-(4-trifluoromethoxyphenyl)-biguanide hydrochloride, and the mixture was refluxed for 9 hours. The solvent was distilled off under reduced pressure, and the residue was recrystallized from hydrous ethanol to obtain 0.7 g of colorless crystals having a melting point of 216 to 220° C.

Provenance & Evidence