Acetone → HCID 178443483, compound

Participants

Reaction Steps

100 ml of methanol, 80 ml of acetone and 0.6 ml of concentrated hydrochloric acid were added to 9.0 g (23.9 mmol) of N1-phenyl-N5-nonyl-biguanide dihydrochloride. The mixture was refluxed for 24 hours, and the solvent was distilled off under reduced pressure. The residue was recrystallized from methyl ethyl ketone to obtain 3.8 g of colorless crystals having a melting of 134 to 137° C.

Provenance & Evidence