反应详情

200 ml of n-propanol was added to 30.0 g (0.16 mol) of 4-methoxyphenethylamine hydrochloride and 14.1 g (0.17 mol) of dicyanodiamide, and the mixture was refluxed for 24 hours, and cooled. The resulting precipitated crystals were filtered off, and the filtrate was concentrated and cooled. The precipitated crystals were recrystallized from n-propanol to obtain 22.6 g of colorless crystals having a melting point of 136 to 139° C.

1. temperaturethe mixture was refluxed for 24 hours
2. temperaturecooled
3. customThe resulting precipitated crystals
4. filtrationwere filtered off
5. concentrationthe filtrate was concentrated
6. temperaturecooled
7. customThe precipitated crystals were recrystallized from n-propanol