HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → (5-Methylcarbamoyl-[1,3,4]oxadiazol-2-ylmethyl)carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ethyl 5-(((tert-butoxycarbonyl)amino)methyl)-1,3,4-oxadiazole-2-carboxylate | HCID 10084542 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (5-Methylcarbamoyl-[1,3,4]oxadiazol-2-ylmethyl)carbamic acid tert-butyl ester | HCID 11777159 | — |
Reaction Steps
Prepared in an analogous fashion to Description 35 from 5-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-1,3,4-oxadiazole-2-carboxylic acid ethyl ester (prepared as described in JOC (1995), 60(10), 3112-20) (0.150 g) using 2.0M methylamine in THF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622464B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-1faecd064f4c494290368abf29dc8b0d |
| Source note | uspto-grants-2009_11 |