HCID 68894402, compound → HCID 68895547, compound

Participants

Reaction Steps

1.87 g of palladium, 10% (dry basis) on activated carbon (50% in water) were added over a solution of 8-48 g (24.7 mmol) of 3-(1-ethoxycarbonyl-1,2,3,6-tetrahydro-pyridinyl) pyrrolo[2,3-b]pyridine-1-carboxylic acid ethyl ester in 250 ml methanol and this mixture was hydrogenated at 2 bar for 20 hours. After filtering through Celite and removing the solvent under reduced pressure, 7.27 g (85% of yield) of the expected product were obtained.

Provenance & Evidence