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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1437189Generated: October 26, 2026

Potassium Hydroxide → 1-furan-3-ylmethyl-3-piperidinyl-1H-pyrrolo[2,3-b]pyridine

https://huagongshe.com/reaction/1437189

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
Reactant4-(1-furan-3-ylmethyl-1H-pyrrolo[2,3-b]pyridin-3-yl) piperidine-1-carboxylic acid ethyl esterHCID 68894772—
Product1-furan-3-ylmethyl-3-piperidinyl-1H-pyrrolo[2,3-b]pyridineHCID 68894745248.8%

Reaction Steps

This compound was prepared following the procedure described in example 24, part D, starting with 4.44 g (11 mmol) of 4-(1-furan-3-ylmethyl-1H-pyrrolo[2,3-b]pyridin-3-yl) piperidine-1-carboxylic acid ethyl ester and 3.6 g of potassium hydroxide. After standard work-up, 3.85 g of 1-furan-3-ylmethyl-3-piperidinyl-1H-pyrrolo[2,3-b]pyridine were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07622480B2
Source datasetuspto-grants-2009_11
ORD IDord-01a7a8dcfd914678b18736c4bff2829c
Source noteuspto-grants-2009_11