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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1437201Generated: October 30, 2026

HCID 17972997, compound → HCID 68893985, compound

https://huagongshe.com/reaction/1437201

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 17972997HCID 17972997—
Reactant5-Bromomethyl-2-methoxybenzoic acid ethyl esterHCID 68893946—
ProductHCID 68893985HCID 6889398543.4%

Reaction Steps

This compound was prepared following the procedure described in example 24, part E, starting with 0.44 g (1.32 mmol) of 1-(5-chlorothiophen-2-ylmethyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine and 0.36 g (1.32 mmol) of 5-bromomethyl-2-methoxybenzoic acid ethyl ester. After standard work-up and purification, 0.3 g (43% yield) of 5-{4-[1-(5-chlorothiophen-2-ylmethyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-piperidin-1-ylmethyl}-2-methoxy-benzoic acid ethyl ester were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07622480B2
Source datasetuspto-grants-2009_11
ORD IDord-73e908c8a6834d2987ca404603725782
Source noteuspto-grants-2009_11