HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 17972997, compound → HCID 68893985, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 17972997 | HCID 17972997 | — |
| Reactant | 5-Bromomethyl-2-methoxybenzoic acid ethyl ester | HCID 68893946 | — |
| Product | HCID 68893985 | HCID 68893985 | 43.4% |
Reaction Steps
This compound was prepared following the procedure described in example 24, part E, starting with 0.44 g (1.32 mmol) of 1-(5-chlorothiophen-2-ylmethyl)-3-piperidin-4-yl-1H-pyrrolo[2,3-c]pyridine and 0.36 g (1.32 mmol) of 5-bromomethyl-2-methoxybenzoic acid ethyl ester. After standard work-up and purification, 0.3 g (43% yield) of 5-{4-[1-(5-chlorothiophen-2-ylmethyl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-piperidin-1-ylmethyl}-2-methoxy-benzoic acid ethyl ester were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622480B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-73e908c8a6834d2987ca404603725782 |
| Source note | uspto-grants-2009_11 |