HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → (R)-tert-Butyl 3-methoxypyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | tert-Butyl (3R)-3-hydroxypyrrolidine-1-carboxylate | HCID 6544479 | — |
| Product | (R)-tert-Butyl 3-methoxypyrrolidine-1-carboxylate | HCID 34179484 | — |
Reaction Steps
The general procedure of Referential Example 106 was repeated through use of (3R)-3-hydroxypyrrolidine-1-carboxylic acid tert-butyl ester (0.955 g) and methyl iodide (0.47 mL), to thereby give the title compound as an oily product (0.899 g, 89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622471B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-428f4183694e49599de3c1e888af986e |
| Source note | uspto-grants-2009_11 |