Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 21873626 | HCID 21873626 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | HCID 21873620 | HCID 21873620 | — |
Reaction Steps
A mixture of the alcohol (e) (971 mg), manganese dioxide (3.72 g), THF (70 ml) and 1,2-dichloroethane (70 ml) was heated at 60° C. under argon for 20 hours. Filtration through kieselguhr and evaporation of solvent gave a solid which was triturated with EtOAc/hexane 1:3 and collected by filtration (608 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07622481B2 |
|---|
| Source dataset | uspto-grants-2009_11 |
|---|
| ORD ID | ord-82ecf590619c4e0eaecbca126800a9e7 |
|---|
| Source note | uspto-grants-2009_11 |
|---|
