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HRID1437360

反应详情

EQUATION

反应方程式

HRID 1437360 的结构方程式

REACTANTS

反应物

3
结构：O=C=O
HCID280

Carbon dioxide

CO2

结构：c1ccc(-c2ccccc2)cc1.c1ccc(Oc2ccccc2)cc1
HCID24670

Phenyl ether-biphenyl mixture

C24H20O

结构：COc1ccc(Br)c(NC=C2C(=O)OC(C)(C)OC2=O)c1
HCID68699062

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(Br)c2[nH]ccc(=O)c12
HCID49757958

8-Bromo-5-methoxyquinolin-4(1H)-one

C10H8BrNO2

收率 76%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

Dowtherm A (30 ml) was heated to reflux and enamine (a) (10 g) was added portionwise (CAUTION—vigorous evolution of CO2 and acetone) over 2 minutes. Heating was continued for a further 2 minutes then the mixture was allowed to cool to room temperature. Filtration and drying in vacuo afforded a brown solid (5.4 g, 76%).

WORKUP

后处理

  1. temperatureto reflux
  2. temperatureHeating
  3. filtrationFiltration
  4. customdrying in vacuo