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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1437364Generated: November 2, 2026

HCID 59427333, compound → 1,4-Dihydro-1,6-naphthyridin-4-one

https://huagongshe.com/reaction/1437364

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59427333HCID 59427333—
Solvent1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene)HCID 24670—
Product1,4-Dihydro-1,6-naphthyridin-4-oneHCID 4089055—

Reaction Steps

Dowtherm A (60 mL) was brought to reflux and (a) (6.3 g, 25.4 mmol) was added portionwise over 2 minutes. The mixture was heated for a further 5 minutes then allowed to cool to room temperature. The resulting solid was washed with a small amount of cold ethanol and dried in vacuo (2.6 g, 69%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07622481B2
Source datasetuspto-grants-2009_11
ORD IDord-81d8a24edc5b4869bbb01293061ff3ff
Source noteuspto-grants-2009_11