HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1437579Generated: November 1, 2026
Benzofuran-2-carboxylic acid → 2,3-Dihydro-1-benzofuran-2-carboxylic acid
https://huagongshe.com/reaction/1437579
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzofuran-2-carboxylic acid | HCID 10331 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2,3-Dihydro-1-benzofuran-2-carboxylic acid | HCID 2776555 | 96.2% |
Reaction Steps
A mixture of 1-benzofuran-2-carboxylic acid (40.0 g, 250.0 mmol) and palladium hydroxide (20 wt. % on carbon, 2.0 g) in acetic acid (400 ml) was heated at 60° C. under a hydrogen atmosphere (80 psi) for 2 h. The mixture was filtered to give a solution of the title compound (39.5 g) in acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07622500B2 |
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| Source dataset | uspto-grants-2009_11 |
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| ORD ID | ord-99e45161e36b436d81e1c1c0182bb7d8 |
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| Source note | uspto-grants-2009_11 |
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