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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1437636Generated: November 1, 2026

2-Bromoacetamide → [cis-4-[[3,5-Bis(trifluoromethyl)benzyl]oxy]-3-phenylpiperidinyl]acetamide

https://huagongshe.com/reaction/1437636

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromoacetamideHCID 69632—
Reactantcis-4-[[3,5-Bis(trifluoromethyl)benzyl]oxy]-3-phenylpiperidine hydrochlorideHCID 86606807—
Product[cis-4-[[3,5-Bis(trifluoromethyl)benzyl]oxy]-3-phenylpiperidinyl]acetamideHCID 8660681452.9%

Reaction Steps

The compound (0.15 g) obtained in Example 1 and bromoacetamide (0.094 g) were reacted and treated in the same manner as in the method described in Example 7 to obtain the title compound as colorless crystals (0.083 g, 52%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07622487B2
Source datasetuspto-grants-2009_11
ORD IDord-fbd390582a6d42d5a954bce27c501cf0
Source noteuspto-grants-2009_11