Methoxyacetic Acid → HCID 86761001, compound

HRID 1437648Notes

Reaction equation

HRID 1437648 reaction equation
Cl.[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[CH:26]=[C:25]([C:33]([F:36])([F:35])[F:34])[CH:24]=2)[CH2:19][CH2:18][NH:17][CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:37][O:38][CH2:39][C:40](O)=[O:41]>>[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:30])([F:31])[F:32])[CH:26]=[C:25]([C:33]([F:36])([F:34])[F:35])[CH:24]=2)[CH2:19][CH2:18][N:17]([C:40](=[O:41])[CH2:39][O:38][CH3:37])[CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 12251Methoxyacetic AcidHCID 86760996HCID 86760996, compound

Product 1

HCID 86761001HCID 86761001, compound

Procedure

The compound (31.8 mg) obtained in Example 25 and methoxyacetic acid (9.2 μl) were reacted and treated in the same manner as in the method described in Example 33 to obtain the title compound.

Workup

  1. additiontreated in the same manner as in the method

Sources & evidence

ORD record
ord-0a168f1638e3479e88879a62eb711a55
Source dataset
uspto-grants-2009_11
Patent number
US07622487B2

Reaction notes

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