N-(tert-butoxycarbonyl)glycine → HCID 69060755, compound

HRID 1437660Notes

Reaction equation

HRID 1437660 reaction equation
Cl.[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[CH:26]=[C:25]([F:33])[CH:24]=2)[CH2:19][CH2:18][NH:17][CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C([NH:41][CH2:42][C:43](O)=[O:44])(OC(C)(C)C)=O>>[CH:2]([C@H:15]1[C@@H:20]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:30])[F:31])[CH:26]=[C:25]([F:33])[CH:24]=2)[CH2:19][CH2:18][N:17]([C:43](=[O:44])[CH2:42][NH2:41])[CH2:16]1)([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 78288N-(tert-butoxycarbonyl)glycineHCID 69059221HCID 69059221, compound

Product 1

HCID 69060755HCID 69060755, compound

Procedure

The compound (28.8 mg) obtained in Example 26 and Boc-glycine (21.0 mg) were reacted and treated in the same manner as in the method described in Example 29 to obtain the title compound.

Workup

  1. additiontreated in the same manner as in the method

Sources & evidence

ORD record
ord-8ff68cd9db9b420a88f5d20dd3168152
Source dataset
uspto-grants-2009_11
Patent number
US07622487B2

Reaction notes

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